Endocrine Abstracts

Objective: Hyperprolactinemia is reported to be associated with impaired glucose metabolism, and low-grade inflammation. There is some data regarding increased oxidative stress- particularly protein oxidation in the conditions like metabolic syndrome or diabetes, but not in hyperprolactinemic subjects in the literature. We aimed to investigate advanced oxidation protein product (AOPP) levels-an established marker of protein oxidation and antioxidant thiol levels in hyperprolac...

Nebivolol is a recently developed beta(1)-selective adrenergic receptor antagonist with proposed nitric oxide mediated vasodilating properties. Effect of nebivolol on vascular smooth muscle has been attributed to estrogen receptor-mediated vascular responsiveness. Although it is known that nitric oxide has relaxing effect on myometrium, there is no report whether nebivolol application affect myometrial contractility. Therefore, we have investigated the effect of nebivolol on r...